Recent publications

 

Tailored Thermoresponsive Polyurethane Hydrogels: Structure–Property Relationships for Injectable Biomedical Applications Di Martino, M., Sessa, L., Romano, F., Piotto, S., Concilio, S. 2025 Polymers 10.3390/polym17172350
Lipidized LL37-loaded PLGA nanocarriers: Bioengineered peptide delivery systems for enhanced wound healing De Soricellis, C., Laigle, C., Spinelli, L., Lollo, G., Del Gaudio, P. 2025 International Journal of Pharmaceutics 10.1016/j.ijpharm.2024.125668
Bending the rules: Molecular dynamics of hydroxylated sphingolipid membranes with 2-hydroxyoleic acid Sessa, L., Concilio, S., Di Martino, M., Busquets, X., Piotto, S. 2025 Chemistry and Physics of Lipids 10.1016/j.chemphyslip.2024.105475
Aerogels based on proteins extracted from plant sources: Different production methodologies Mottola, S., Cardea, S., Montella, F., De Marco, I., Ersus, S. 2025 Food and Bioproducts Processing 10.1016/j.fbp.2024.08.015
Optimizing mRNA delivery: A microfluidic exploration of DOTMA vs. DOTAP lipid nanoparticles for GFP expression on human PBMCs and THP-1 cell line Lamparelli, E.P., Ciaglia, E., Ciardulli, M.C., Puca, A.A., Della Porta, G. 2025 International Journal of Pharmaceutics 10.1016/j.ijpharm.2024.125324
Hybrid lipid nanoparticles derived from human mesenchymal stem cell extracellular vesicles by microfluidic sonication for collagen I mRNA delivery to human tendon progenitor stem cells Pareja Tello, R., Lamparelli, E.P., Ciardulli, M.C., Della Porta, G., Santos, H.A. 2025 Biomaterials Science 10.1039/d4bm01632a
Supercritical CO2 particulate leaching and impregnation: A new strategy for customized electrospun mats loaded with an antiviral drug Mottola, S., Drago, E., Campardelli, R., De Marco, I. 2025 Chemical Engineering Journal 10.1016/j.cej.2024.160262
Pectin/alginate aerogel containing ZnO produced from beetroot extract mediated green synthesis for potential applications in food packaging Mottola, S., Viscusi, G., Oliva, G., Gorrasi, G., De Marco, I. 2025 Journal of Co2 Utilization 10.1016/j.jcou.2024.102858
Human tendon stem/progenitor cell-derived extracellular vesicle production promoted by dynamic culture Clerici, M., Ciardulli, M.C., Lamparelli, E.P., Maffulli, N., Della Porta, G. 2025 Artificial Cells Nanomedicine and Biotechnology 10.1080/21691401.2024.2413282
Tenogenic Cues Are Biochemically and Environmentally Distinct for Tendon Stem Cells and Mesenchymal/Stromal Stem Cells Citro, V., Clerici, M., Porta, G.D., Dale, T.P., Forsyth, N.R. 2025 Stem Cells International 10.1155/2025/9047956
ColMA-based bioprinted 3D scaffold allowed to study tenogenic events in human tendon stem cells Cortella, G., Lamparelli, E.P., Ciardulli, M.C., Maffulli, N., Della Porta, G. 2025 Bioengineering and Translational Medicine 10.1002/btm2.10723
PLA/PLGA nanocarriers fabricated by microfluidics-assisted nanoprecipitation and loaded with Rhodamine or gold can be efficiently used to track their cellular uptake and distribution Lamparelli, E.P., Marino, M., Scognamiglio, M.R., Santoro, A., Della Porta, G. 2024 International Journal of Pharmaceutics 10.1016/j.ijpharm.2024.124934
Designing Microparticles of Luteolin and Naringenin in Different Carriers via Supercritical Antisolvent Process Mottola, S., De Marco, I. 2024 Polymers 10.3390/polym16243600
Enhanced mitigation of VOCs, CO2 and odour emissions from organic fraction of solid waste using innovative biodegradable patches generated by supercritical carbon dioxide impregnation De Paola, S., Mottola, S., Oliva, G., Naddeo, V., De Marco, I. 2024 Case Studies in Chemical and Environmental Engineering 10.1016/j.cscee.2024.100866
Production and simulated digestion of high-load beads containing Schizochytrium oil encapsulated utilizing prilling technique Beltrame, G., Damerau, A., Ahonen, E., Del Gaudio, P., Linderborg, K.M. 2024 Food Chemistry 10.1016/j.foodchem.2024.140694
Hybrid nano-carrier of citral in starch composites for potential application in active packaging Viscusi, G., Lamberti, E., Boccalon, E., Nocchetti, M., Gorrasi, G. 2024 Applied Clay Science 10.1016/j.clay.2024.107550
Application of electrospun N-doped carbon dots loaded cellulose acetate membranes as cationic dyes adsorbent Mottola, S., Viscusi, G., Tohamy, H.-A.S., Gorrasi, G., De Marco, I. 2024 Journal of Environmental Management 10.1016/j.jenvman.2024.122714
Fibrin Scaffolds Perfused with Transforming Growth Factor-β1 as an In Vitro Model to Study Healthy and Tendinopathic Human Tendon Stem/Progenitor Cells Ciardulli, M.C., Lovecchio, J., Parolini, O., Maffulli, N., Della Porta, G. 2024 International Journal of Molecular Sciences 10.3390/ijms25179563
Hyaluronate loaded advanced wound dressing in form of in situ forming hydrogel powders: Formulation, characterization, and therapeutic potential Amante, C., Neagu, M., Falcone, G., Nicolais, L., Del Gaudio, P. 2024 International Journal of Biological Macromolecules 10.1016/j.ijbiomac.2024.133192
Production of mono and bilayer devices for wound dressing by coupling of electrospinning and supercritical impregnation techniques Mottola, S., Viscusi, G., Belvedere, R., De Marco, I., Gorrasi, G. 2024 International Journal of Pharmaceutics 10.1016/j.ijpharm.2024.124308
Efficiency of dye adsorption of modified biochar: A comparison between chemical modification and ball milling assisted treatment Lamberti, E., Viscusi, G., Kiani, A., Acocella, M.R., Gorrasi, G. 2024 Biomass and Bioenergy 10.1016/j.biombioe.2024.107247
Cationic Azobenzenes as Light-Responsive Crosslinkers for Alginate-Based Supramolecular Hydrogels Di Martino, M., Sessa, L., Panunzi, B., Piotto, S., Concilio, S. 2024 Polymers 10.3390/polym16091233
Two series of benzofuran and benzodifuran chelating chromophores with DR/NIR emission and anticancer activity Diana, R., Schibeci, M., Arciello, A., Caruso, U., Panunzi, B. 2024 Dyes and Pigments 10.1016/j.dyepig.2023.112034
Ligand-Free Silver Nanoparticles: An Innovative Strategy against Viruses and Bacteria Morone, M.V., Chianese, A., Dell’Annunziata, F., Galdiero, M., Morone, A. 2024 Microorganisms 10.3390/microorganisms12040820
Biomimetic proteolipid vesicles for reverting GPI deficiency in paroxysmal nocturnal hemoglobinuria Giudice, V., Scala, P., Lamparelli, E.P., Della Porta, G., Selleri, C. 2024 Iscience 10.1016/j.isci.2024.109021
Curcumin/Carrier Coprecipitation by Supercritical Antisolvent Route Mottola, S., De Marco, I. 2024 Pharmaceutics 10.3390/pharmaceutics16030352
Production of inclusion complexes containing corticosteroids by SAA process Mottola, S., De Marco, I. 2024 Journal of Supercritical Fluids 10.1016/j.supflu.2023.106115
Advancements and novel approaches in modified AutoDock Vina algorithms for enhanced molecular docking Sarkar, A., Concilio, S., Sessa, L., Marrafino, F., Piotto, S. 2024 Results in Chemistry 10.1016/j.rechem.2024.101319
Supercritical Antisolvent Precipitation of Corticosteroids/β-Cyclodextrin Inclusion Complexes Mottola, S., De Marco, I. 2024 Polymers 10.3390/polym16010029
Design of Cellulose Acetate Electrospun Membranes Loaded with N-doped Carbon Quantum Dots for Water Remediation Viscusi, G., Mottola, S., Tohamy, H.-A.S., Gorrasi, G., De Marco, I. 2024 Lecture Notes in Civil Engineering 10.1007/978-3-031-39667-5_13
In Situ Hydrogel Formulation for Advanced Wound Dressing: Influence of Co-Solvents and Functional Excipient on Tailored Alginate–Pectin–Chitosan Blend Gelation Kinetics, Adhesiveness, and Performance Amante, C., Falcone, G., Aquino, R.P., Nicolais, L., Del Gaudio, P. 2024 Gels 10.3390/gels10010003
Supercritical impregnation of starch aerogels with quercetin: Fungistatic effect and release modelling with a compartmental model Mottola, S., Iannone, G., Giordano, M., Martín del Valle, E., De Marco, I. 2023 International Journal of Biological Macromolecules 10.1016/j.ijbiomac.2023.127406
The Other Side of Plastics: Bioplastic-Based Nanoparticles for Drug Delivery Systems in the Brain Lamparelli, E.P., Marino, M., Szychlinska, M.A., Della Porta, G., Santoro, A. 2023 Pharmaceutics 10.3390/pharmaceutics15112549
Theoretical investigation of hydroxylated analogues of valinomycin as potassium transporter Sessa, L., Concilio, S., Marrafino, F., Diana, R., Piotto, S. 2023 Computational Biology and Chemistry 10.1016/j.compbiolchem.2023.107936
Endotenon-Derived Type II Tendon Stem Cells Have Enhanced Proliferative and Tenogenic Potential Clerici, M., Citro, V., Byrne, A.L., Maffulli, N., Forsyth, N.R. 2023 International Journal of Molecular Sciences 10.3390/ijms242015107
GUIDE: A GUI for automated quantum chemistry calculations Sarkar, A., Sessa, L., Marrafino, F., Piotto, S. 2023 Journal of Computational Chemistry 10.1002/jcc.27213
Transdermal Patches Containing Opioids in the Treatment of Patients with Chronic Pain De Marco, I. 2023 Processes 10.3390/pr11092673
Production of Antioxidant Transfersomes by a Supercritical CO2 Assisted Process for Transdermal Delivery Applications Squittieri, R., Baldino, L., Reverchon, E. 2023 Nanomaterials 10.3390/nano13121812
Supercritical Impregnation of Mesoglycan and Lactoferrin on Polyurethane Electrospun Fibers for Wound Healing Applications Mottola, S., Viscusi, G., Iannone, G., De Marco, I., Gorrasi, G. 2023 International Journal of Molecular Sciences 10.3390/ijms24119269
Activity and Selectivity of Novel Chemical Metallic Complexes with Potential Anticancer Effects on Melanoma Cells Ciardulli, M.C., Mariconda, A., Sirignano, M., Della Porta, G., Longo, P. 2023 Molecules 10.3390/molecules28124851
Contribution of peripheral blood mononuclear cells isolated by advanced filtration system to myogenesis of human bone marrow mesenchymal stem cells co-cultured with myoblasts Scala, P., Manzo, P., Longo, R., Maffulli, N., Della Porta, G. 2023 Heliyon 10.1016/j.heliyon.2023.e17141
Recent Progress in Photoresponsive Biomaterials Di Martino, M., Sessa, L., Diana, R., Piotto, S., Concilio, S. 2023 Molecules 10.3390/molecules28093712
Removal of Azo Dyes from Wastewater through Heterogeneous Photocatalysis and Supercritical Water Oxidation Vaiano, V., De Marco, I. 2023 Separations 10.3390/separations10040230
Coprecipitation of Class II NSAIDs with Polymers for Oral Delivery De Marco, I. 2023 Polymers 10.3390/polym15040954
A new serotonin 2A receptor antagonist with potential benefits in Non-Alcoholic Fatty Liver Disease Sessa, L., Concilio, S., Fominaya, J., Piotto, S., Busquets, X. 2023 Life Sciences 10.1016/j.lfs.2023.121315
A DR/NIR Hybrid Polymeric Tool for Functional Bio-Coatings: Theoretical Study, Cytotoxicity, and Antimicrobial Activity Diana, R., Gentile, F.S., Concilio, S., Di Costanzo, L., Panunzi, B. 2023 Polymers 10.3390/polym15040883
Peripheral blood mononuclear cells contribute to myogenesis in a 3D bioengineered system of bone marrow mesenchymal stem cells and myoblasts Scala, P., Manzo, P., Lamparelli, E.P., Maffulli, N., Della Porta, G. 2023 Frontiers in Bioengineering and Biotechnology 10.3389/fbioe.2022.1075715
Bottom-Up Strategy to Forecast the Drug Location and Release Kinetics in Antitumoral Electrospun Drug Delivery Systems Longo, R., Raimondo, M., Vertuccio, L., Della Porta, G., Guadagno, L. 2023 International Journal of Molecular Sciences 10.3390/ijms24021507
Tendon tissue engineering: An overview of biologics to promote tendon healing and repair Citro, V., Clerici, M., Boccaccini, A.R., Maffulli, N., Forsyth, N.R. 2023 Journal of Tissue Engineering 10.1177/20417314231189817
Vapor–Liquid Equilibria of Quaternary Systems of Interest for the Supercritical Antisolvent Process Campardelli, R., Mottola, S., De Marco, I. 2022 Processes 10.3390/pr10122544
3D in-vitro cultures of human bone marrow and Wharton’s jelly derived mesenchymal stromal cells show high chondrogenic potential Lamparelli, E.P., Ciardulli, M.C., Giudice, V., Maffulli, N., Della Porta, G. 2022 Frontiers in Bioengineering and Biotechnology 10.3389/fbioe.2022.986310
Supercritical Fluids and Nanoparticles in Cancer Therapy De Marco, I. 2022 Micromachines 10.3390/mi13091449
Production of Mesoglycan/PCL Based Composites through Supercritical Impregnation Liparoti, S., Mottola, S., Viscusi, G., Pantani, R., De Marco, I. 2022 Molecules 10.3390/molecules27185800
Azobenzene as Antimicrobial Molecules Di Martino, M., Sessa, L., Di Matteo, M., Piotto, S., Concilio, S. 2022 Molecules 10.3390/molecules27175643
Synthesis and Characterization of a Novel Composite Scaffold Based on Hyaluronic Acid and Equine Type I Collagen Lamparelli, E.P., Casagranda, V., Pressato, D., Della Porta, G., Bellini, D. 2022 Pharmaceutics 10.3390/pharmaceutics14091752
Lipid nano-vesicles for thyroid hormone encapsulation: A comparison between different fabrication technologies, drug loading, and an in vitro delivery to human tendon stem/progenitor cells in 2D and 3D culture Lamparelli, E.P., Ciardulli, M.C., Scala, P., Maffulli, N., Della Porta, G. 2022 International Journal of Pharmaceutics 10.1016/j.ijpharm.2022.122007
Stem Cells from Healthy and Tendinopathic Human Tendons: Morphology, Collagen and Cytokines Expression and Their Response to T3 Thyroid Hormone Ciardulli, M.C., Scala, P., Giudice, V., Maffulli, N., Porta, G.D. 2022 Cells 10.3390/cells11162545
Production of carrier/antioxidant particles by Supercritical Assisted Atomization as an adjuvant treatment of the CoVID-19 pathology De Marco, I. 2022 Journal of Supercritical Fluids 10.1016/j.supflu.2022.105604
Electrospun Membranes Designed for Burst Release of New Gold‐Complexes Inducing Apoptosis of Melanoma Cells Guadagno, L., Raimondo, M., Vertuccio, L., Della Porta, G., Longo, R. 2022 International Journal of Molecular Sciences 10.3390/ijms23137147
Multifaceted Analyses of Isolated Mitochondria Establish the Anticancer Drug 2-Hydroxyoleic Acid as an Inhibitor of Substrate Oxidation and an Activator of Complex IV-Dependent State 3 Respiration Mishra, K., Péter, M., Nardiello, A.M., Piotto, S., Kakhlon, O. 2022 Cells 10.3390/cells11030578
ARISE: Artificial Intelligence Semantic Search Engine Di Biasi, L., Santoro, J., Piotto, S. 2022 Communications in Computer and Information Science 10.1007/978-3-031-02605-5_16
YAMACS: a graphical interface for GROMACS Sarkar, A., Santoro, J., Biasi, L.D., Marrafino, F., Piotto, S. 2022 Bioinformatics 10.1093/bioinformatics/btac565
Artificial Chemical Neural Network for Drug Discovery Applications Piotto, S., Sessa, L., Santoro, J., Di Biasi, L. 2022 Communications in Computer and Information Science 10.1007/978-3-031-02605-5_19
Zein electrospun fibers purification and vanillin impregnation in a one-step supercritical process to produce safe active packaging Drago, E., Franco, P., Campardelli, R., De Marco, I., Perego, P. 2022 Food Hydrocolloids 10.1016/j.foodhyd.2021.107082
Myogenic commitment of human stem cells by myoblasts Co-culture: a static vs. a dynamic approach Scala, P., Lovecchio, J., Lamparelli, E.P., Maffulli, N., Della Porta, G. 2022 Artificial Cells Nanomedicine and Biotechnology 10.1080/21691401.2021.2011976
Environmental and sustainability analysis of a supercritical carbon dioxide-assisted process for pharmaceutical applications Trucillo, P., Campardelli, R., De Marco, I. 2021 Processes 10.3390/pr9101788
Stem cell and macrophage roles in skeletal muscle regenerative medicine Scala, P., Rehak, L., Giudice, V., Porta, G.D., Maffulli, N. 2021 International Journal of Molecular Sciences 10.3390/ijms221910867
Effect of the carrier on the coprecipitation of curcumin through supercritical-assisted atomization De Marco, I., Franco, P. 2021 Chemengineering 10.3390/chemengineering5030059
3d biomimetic scaffold for growth factor controlled delivery: An in-vitro study of tenogenic events on wharton’s jelly mesenchymal stem cells Ciardulli, M.C., Lovecchio, J., Scala, P., Maffulli, N., Porta, G.D. 2021 Pharmaceutics 10.3390/pharmaceutics13091448
Evaluating epidemiological risk by using open contact tracing data: Correlational study Piotto, S., Di Biasi, L., Marrafino, F., Concilio, S. 2021 Journal of Medical Internet Research 10.2196/28947
Porous aerogels and adsorption of pollutants from water and air: A review Franco, P., Cardea, S., Tabernero, A., De Marco, I. 2021 Molecules 10.3390/molecules26154440
Biotransformation of silver nanoparticles into oro-gastrointestinal tract by integrated in vitro testing assay: Generation of exposure-dependent physical descriptors for nanomaterial grouping Carnovale, C., Guarnieri, D., Di Cristo, L., Pompa, P.P., Sabella, S. 2021 Nanomaterials 10.3390/nano11061587
Supercritical carbon dioxide-based processes in photocatalytic applications Franco, P., Sacco, O., Vaiano, V., De Marco, I. 2021 Molecules 10.3390/molecules26092640
Contact lenses as ophthalmic drug delivery systems: A review Franco, P., De Marco, I. 2021 Polymers 10.3390/polym13071102
Amnion-Derived Teno-Inductive Secretomes: A Novel Approach to Foster Tendon Differentiation and Regeneration in an Ovine Model Citeroni, M.R., Mauro, A., Ciardulli, M.C., Forsyth, N.R., Barboni, B. 2021 Frontiers in Bioengineering and Biotechnology 10.3389/fbioe.2021.649288
Chondrogenic commitment of human bone marrow mesenchymal stem cells in a perfused collagen hydrogel seeded with hTGF-β1-releasing PLGA microcarrier Lamparelli, E.P., Lovecchio, J., Ciardulli, M.C., Maffulli, N., Porta, G.D. 2021 Pharmaceutics 10.3390/pharmaceutics13030399
Supercritical emulsion extraction fabricated PLA/PLGA micro/nano carriers for growth factor delivery: Release profiles and cytotoxicity Palazzo, I., Lamparelli, E.P., Ciardulli, M.C., Santoro, A., Della Porta, G. 2021 International Journal of Pharmaceutics 10.1016/j.ijpharm.2021.120108
Study of the interaction of a novel semi-synthetic peptide with model lipid membranes Sessa, L., Concilio, S., Walde, P., Caruso, U., Piotto, S. 2020 Membranes 10.3390/membranes10100294